This is an easy decision IMO.
If you are in love with The Samsung/Touchwiz experience & Apps, get the Note.
If you like having full access to every aspect of your phone and enjoy tweaking/playing with roms and general advantages of vanilla android, get the Nexus.
I've had a few generations of notes and loved them, other than the inability to completely unlock the phone, and I'm sort of done with that now. Having lots of fun on the nexus.