I think he would do fine there, but USC is known for great QBs when they are good and Les has struggling more than any good coach I can think of in College Football with recruiting a decent quarterback.
I think Penn State would be perfect for Les. It's relatively close to his hometown (Elyria, Ohio) and Penn State is very similar in a lot of ways to LSU as far as traditional style of play. I would love for him to come to the B1G. That would absolutely solidify the B1G as the conference with the best coaches if it isn't already.