Rt 2/90 isn't to bad once you get closer to the sandusky area, probably your best bet. the parts of 6 I have been on is 1 lane each direction and the fucking tourist don't know how to drive. I will probably be coming up from columbus and staying with my parents over in Port Clinton. If people want to meet up later or some thing the Toys R Us off of 250 in Sandusky has always been pretty bike friendly and has a lot of empty parking lot space.