I've had a panel style interview before myself. They can really get your nerves going, man, you need to relax though. Here's the deal with interviews like this: the likelihood of everyone wanting to hire you is slim. Someone is bound to not like the way you come off. You should be able to identify the people you are meshing with quickly, when you do, tailor yourself a little more to spark up something with them, get them engaged. Pick that person(s) you are identifying well with and when you are responding to questions look toward them for the majority of the time if it makes you feel more comfortable. However, do try to address everyone.
When I've dealt with similar situations I do the obvious: learn about the company, get a good nights rest and a good meal, a haircut, and practice slangin' bs. I would suggest writing 5 questions to ask them, as well, don't let them do all the talking. When they ask "do you have any questions for us?" hit'em.
So, where you interviewing bruh?