My grandparents have a 2010ish Honda Odyssey with 200k on it (they live near Hillsboro, OH, so literally every time they leave the garage it's 30+ miles on the vehicle, and gobs more if they want to go to an actual city) and it runs like a champ. Zero issues, just regular vehicle maintenance. It's pretty nicely loaded, super comfy, quite roomy, and gets great gas mileage for a vehicle so "big".