My very good friend took a job in Vegas 5 months ago with Unilever. He is a single guy with no kids and has loved the move out there. He lives near Lake Las Vegas and he loves it. That area is far enough away from the strip that you do not need to deal with it, but close enough if you want to go down there. There is a lot of different things to do out there, ie boating at Lake Mead, Bureau of Land Management off roading travels if you have a truck, guns are big out there and you can shoot in the desert with minor restrictions, Skiing is not that far either if you are in to that and golf is amazing out there. I don't know how well it would be for a family, but if your in the place and time in your life to do it I would.
I also met a bunch of his co-workers who were all from the mid-west and east coast. It seems that most people go out there, work for a couple years and then go back home.
Good luck with the process, it is never easy but I'm sure you will make the right decision.