Possibly. I mean, it MIGHT be feasible. It's not all that different from folks I've talked to that drive to Columbus from Portsmouth or even WV for work.
Sure, there's a MASSIVE cost in the travel, but when the only jobs down there pay min wage and offer no perks or bene's, landing a job in Columbus that pays double, triple, etc. makes it worthwhile to them.
No, I wouldn't travel that far, but some do. Half hour to Chicago where I could get paid triple or whatever? I'd look into it.