Those are some great roads. Here's a trip report from 2014 with some road conditions and comments related to some of the roads on your map. Thought it might be useful. I have a 3 day WV trip planned in a couple weeks. I'll post details on road conditions afterward.
Day one starting from Marietta. 47
16
39
219/55
47 was a good connector route and got us warmed up. 16 is a very twisty road. There were times that I was hoping a straight would be coming so I could rest. Road quality is a huge hodge podge. Kind of rough up north, then you'd hit nice pavement, then you'd hit brand new pavement then back to rough. It was really all over the place. The rough parts could be bone jarring but not impassable so I'd still recommend the road, just be cautious in the bad parts. 39 was fun and in decent shape from what I could remember. 218/55 were also in good shape and had some really nice sections. Day 2 from Elkins 33 south. It was so much fun we turned around and did it again. Southern part of 33 is amazing. Lots of new pavement and if it wasn't new, it was in great shape. 33 is a must!!!! from 33 to 28 - ok connector road but not as curvy as I thought it would be. It was interesting though as you were riding between the two mountains so I would call it scenic. 28 to 250 south - 250 was a very good road. I definitely want to do the whole section at some point. I was worried about road conditions and found this part to be completely fine so I would think the other sections in this area are probably OK as well. 250 to 220 - 220 was really not that exciting. We were actually pretty mellow on this road and of course, this is where we get tickets. A speeding ticket for both of us and passing on double yellow for me as a bonus. Thank you Virginia! After this joyous detour, I wanted to get out of Virginia as soon as possible so we picked up 39 north. What a nice road!! Freshly paved in most spots and just really twisty. I would have enjoyed it even more if we hadn't just gotten the darn tickets but it was really fun. 39 is another must route. Took 39 to 92 and then over to Beckley. We almost ran out of gas in this area and GPS tried to take us down a crazy road. There were lots of adv tour type of roads in this area for those that might be interested. Day 3 From Beckley heading back to Marietta 41 to 19 to 60 Over to 61 16 36 14 41 is a dump. The road quality is beyond poor. They had neon red circles and lines all over the road highlighting pot holes and other deformities. Felt like I was at Nelson Ledges but worse. Until they pave this thing, I would avoid it. 61 near Deepwater is a blast!!!!!! Brand new pavement and just wow! Good times. Keep in mind, unless you are on an adv tour bike, you will need to go to the town to cross the river. We tried heading over to another crossing and the road was crazy bad. I think the town is Montgomery? 36 is a pretty fun road. There are several parts that are freshly paved. It's a really nice north/south route. 14 is a decent connector road. Decent amount of turns and pavement is good for the most part although there are some bad spots.