I have a V10. 05 F250. as long as you DO NOT GET THE 4.30 GEARS, its not that much worst than a Diesel. I've driven 16000 since September. I can get over 16 MPG on the interstate. and i still get 15 with a flat trailer behind me. It drops to 12 with a 18ft v nose trailer behind it. I work very closely with another guy who has a '11 F250 with the 6.7L Diesel. he gets 18 Highway and his drops to 12 with his 24' vnose. Most these other guys don't have the first hand experience I do. The front ends are notorious in these truck. get the dual stabilizer the first time it needs it and be done. there is no reason it needs to be redone every 2 years. You dont need a 350 and will get worse gas milage just because its that much heavy that the 250. As far as the V10. It had some troubles in the first year (03) but they worked those out. and has proven to be reliable till 300,000+ miles.