YES and if you can't wrap your head around that you should PROBABLY not be allowed to vote. It's your responsibility as an informed voter to know the fucking difference, not to say "SO WHAT IT'S NOT THAT BIG A DEAL WE'LL LET FUTURE GENERATIONS FIGURE THAT CLUSTERFUCK OUT".
There are many good reasons to vote yes on 3. There are about 10x more good reasons to vote no. If you have to ask if it's really that big a deal, consider also asking yourself "why, when making a law would be much simpler and easier to pass, would they spend so much time, money, and effort to instead push it through as a constitutional amendment? what do they stand to gain from the difference? should I maybe take a step back to analyze this issue more than 'weed should be legal'?"