Beware the Kimber... Nothing but issues from them in the last two years.
I prefer the 45 ACP. EASIER AND CHEAPER TO GET AMMO FOR. If it was my only gun for carry, that would be the selling point.
On the other hand, 10MM is great. I love it. Perfect round, but you will pay to shoot it and it isn't the easiest to procure.
10mm never won any accuracy competitions, but it is accurate. check out double tap ammo for more information.