555 is a GREAT road if you like a very technical route. Lots of twists, turns, hills, and hollows. More blind curves than most people like. I love the southern end (which has lots of them).
There are very few places where water will sit thanks to all the elevation changes. But all of those hollows mean that you will have quite a few curves that pass through shaded areas that will not see any sun till late in the day. So with 20's in the evening and then only getting up to 32, I'd be very concerned about icy spots. Also, if we get the snow they're predicting for Friday - at least here in WV, then ODOT will be out spreading sand. Out in the country they put it just in the critical spots - which can be surprising. That would not be fun at all.
If you want to get out Friday, I'd stick to the 4 lanes like 33, 50, then 23 back to C'bus. Unless those roads also have a coating of sand and salt...
Spring is on the way!