Crossing state lines with a gun = shooting yourself in the dick????
Negative. There's a sticky about this in the gun section for a reason...
https://en.wikipedia.org/wiki/Firearm_Owners_Protection_Act
Since you are crossing state lines, the federal gov actually did something smart for once. The problem is that state cops would probably still try to nail you for whatever they can if they happen to find you in their jurisdiction, but federal law would bail you out so long as you were following it. I don't see how (or why I should have to) get an Indiana permit to transport a firearm if I don't live in Indiana. Or why I couldn't drive to Vermont or New Hampshire with an AR, passing through NY. Or why I couldn't drive through Colorado on my way to Nevada with 30 round PMAGs. Just have to make sure everything is inaccessible without getting out of the car or, if there's no trunk, unlocking the case, and everything is unloaded, and you are fine.