Here is an uber twisty 2 day OH/WV route. Elkins is a decent place to spend the night. Just avoid the Days Inn, it was concerted from an old hospital. I kind of feels like an asylum. The Holiday in is much nicer. Bolivar, OH to Elkins, WV and back Day 1 1.OH-93 S 2.OH-83 S 3.OH-78 W 4.OH-377 S 5.OH-550 E 6.OH-7 E 7. I-77 S into West Virginia 8. Take exit 174 for W Virginia 47/Staunton Ave 9.WV-47 E 10. WV-16 S; Continue onto US-119 S/US-33 W/WV-16 S 11. US-60 E/Midland Trail 12.WV-20 N 13.WV-15 E 14. US-219 N; Continue onto US-219 N/US-250 N/WV-55 E/WV-92 N 15. WV-92 N/Harrison Ave. Arriving at: Days Inn and Suites Elkins 1200 Harrison Ave, Elkins, WV 0.9 mi NW (304) 637-4667 Day 1 Total: 449 mi - about 10 hours 58 mins Day2 US-219 S/WV-92 S US-33 E/WV-55 E; US-33 E/WV-28 S; US-33 E US-220 S/US-33 E; Continue to follow US-220 S into Virginia US-250 E into West Virginia; US-250 N/WV-92 N US-219 S/WV-55 W WV-15 W WV-20 N; US-19 N/WV-20 N/W Pike St ramp; Continue onto WV-20 N WV-7 W WV-2 N entering Ohio OH-7 N OH-556 W OH-145 OH-148 W OH-800 N; OH-800 N/US-250 W; Continue to follow US-250 W I-77 NDay 2 Total: 419 mi - about 10 hours 6 mins That's about as many corners as you can squeeze into 2 days. You can reach some other excellent roads if you add a 3rd day.