Starting back out 50 lbs each hand is too much. If your out of shape then your muscles are out of shape and that means energy supply routes have been reduced. Your joints also have changed and heavy weights all of a sudden can tear ligaments or weaken tendons. Then lifting will really suck. So focus less on hypertrophy and get endurance first. Something simple like tonight do 25x2 sit ups, 25x2 pushups, 20lbs each hand at 10x5 curls and overhead, 50lb bar bench at 5x5. See how your body feels and increase by 5 lbs next workout if desired. But tomorrow, go walk, light jog, bicycle, tread mill if you have one for 20 min, 1 hour after dinner. Alternate the days exercise with Saturday or Sunday as a day off if needed. By increasing in increments you are less likely to overdo it and able to adjust down in weight if needed. Same for the cardio days. Sounds easy but starting out the biggest issue is getting into a habit of doing it. Results will come