My mother has Multiple Sclorosis and constant severe sciatic nerve pain. Although she would never use it, I have read a lot of articles about marijuana use benefitting people affected by a chronic issue.
Part of the issue in my opinion is the general public being lied to about the effects of marijuana. While some side effects told are true, many are not. My thinking always reverts to my experiences with pot users, most are very relaxed and still fairly productive people compared to an alcoholic. If they have a legitimate reason to use cannibis other than to just get stoned, I'm for it. I know far fewer people with a "marijuana problem" than a drinking problem, every alcoholic I know is almost to the point of self loathing and minimal productivity. We have one of each in my shop, one of which turns good hours, the alcoholic...though..He is lucky to make 15-22.
For me it is a no brainer. If anything start with medical marijuana, to get our feet wet so to speak, then possibly branch out into 100% legality assuming things go well.