Bad has it right, sort of. From Dayton Louisville isn't a bad run. It's awesome. Stay at the Hyatt Louisville downtown. Right on 4th street in the center of all the action, it's awesome down there. Tons of stuff to do. Eat at Doc Crow's, easily walkable from the Hyatt. Get a pound of the Cajun/BBQ shrimp.
If you have a good line of BS, call the Hyatt direct. Tell them you are one of the people that work for 'Derbycon' and you are coming down with your wife for a vaca. You should get a killer deal. FYI for your story, Derbycon is a hacker convention my kid runs down there. He sells the hotel out for a week...spends a BOATLOAD of money there. They should hook you up.